Academic Research
Get the Best out of Your Nucleic Acid Extraction
Applications such as sequencing, PCR, cloning, gene editing, and epigenetics belong to the molecular biology researcher's "standard toolbox" and high quality nucleic acids build the foundation of great results. Nucleic acid extraction is one of the most pivotal and self-evident steps in molecular biology, as it is widely and routinely used in many areas of the biological and medical sciences.
Despite the prevalence of nucleic acid extraction methods, workers in these areas cope daily with low DNA quality and yield, have to deal with toxic substances, and must address the increasing need for a reasonable rate of consumable consumption as well as to manage cost targets.
To master these challenges, BioEcho is committed to support you with nucleic acid extraction solutions applicable for a wide range of routine applications from your "standard toolbox". Our solutions support you to isolate and purify DNA and RNA quickly, cost-effectively and with high yield and purity – even for challenging samples. With less consumable consumption you can significantly reduce your environmental footprint.
Making high-quality nucleic acid extraction faster and simpler
Speed up & simplify your nucleic acid extraction
Tedious bind–wash–elute procedures build a bottleneck in daily routines. Our EchoLUTION technology relies on single-step nucleic acid isolation within a one-minute centrifugation. Nucleic acids pass through the purification matrix without interaction, while impurities are held back and are completely removed. Different from the conventional silica-based bind–wash–elute nucleic acid extraction methods, EchoLUTION allows today’s fastest and simplest nucleic acid extraction with the highest purity.
Faster to result
Fewer protocol steps with our one-minute extraction technology
Inhibitor-free nucleic acids
High quality for reliable and reproducible downstream applications
High yield
Excellent recovery and high concentration across various tissues and sample types
Superior for challenging samples
Make DNA accessible even with difficult species, tissues and sample types.
Reduced consumable costs
Less consumable consumption due to less workflow steps compared to other methods
Fewer toxic reagents
Toxic reagents are replaced with environmentally friendly alternatives.
Extracting DNA from animal sample types or plant cells often results in an unfavorable gDNA yield and purity for downstream applications. Differences in cell numbers for blood between animal species lead to a reduced yield. In plants, rigid cell walls must be lysed appropriately in order to expose the cytoplasm. Native DNA contaminants affect the quality of isolated DNA and can inhibit downstream enzymatic reactions.
Our EchoLUTION extraction technology involves a lysis step that is tailored to animal or plant sample types allowing for an efficient lysis and purification to avoid carryover of contaminants.
Particularly in experiments, where sensitivity is of high importance (such as qPCR with limited sample material), EchoLUTION-purified DNA outperforms results obtained with the silica-based technology.
Up to fivefold more DNA yield than with silica-based kits
No native DNA contaminants
No toxic substances or chaotropic salts that inhibit downstream applications
Increase purity & yield across different species and sample types
Featured Resource
DNA extraction from mammalian cells
Researchers from TU Braunschweig extracted total DNA from a wide range of mammalian cell preparations and tissues.
Nucleic acid extraction solutions
Featured Publications
gDNA extraction from embryonic stem cells
Researchers at the University Bonn investigated an inducible overexpression system in mouse embryonic stem cells. The EchoLUTION Cell Culture Kit was used to extract the genomic DNA, which was used to determine copy number by qPCR.
Bee gDNA extraction for NGS
Husemann et al. researched the mitogenomic phylogeny of bee families. The DNA extraction was performed with the EchoLUTION Blood DNA HiYield Kit for NGS-library preparation.
Barley gDNA extraction for genotyping
Scientists from Spain and Hungary researched the responses of barley to high ambient temperatures. The BioEcho Plant DNA Kit was used for genomic DNA extraction for amplifications, KASP assays, and whole-genome genotyping.
Guppy gDNA extraction for microsatellite genotyping
Charlesworth et al. researched the evolution of the guppy Y chromosome. The authors used the EchoLUTION Tissue DNA Kit to extract gDNA for microsatellite genotyping.
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University of Edinburgh
“We are using BioEcho’s Tissue DNA Micro kit successfully and on a regular basis for DNA isolation from fish tissue samples.”Jim Gardner, University of Edinburgh
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AIM GmbH, Leipzig, Germany
“We at Advanced Identification Methods (AIM) are specialized in the analyses of the biodiversity of our environment using genomic methods. For example, we analyze bulk samples derived from insect traps and mixed plant, wood, and soil samples by extracting the total DNA from the biological samples and a subsequent identification of individuals present by DNA metabarcoding. We have thoroughly tested the EchoLUTION DNA extractions kits for animal tissue and plant materials and use these very successfully in our routine workflows. Besides the technical reliability of the kits, we like the sustainability approach of BioEcho a lot. Using their kits, we save a lot of plastic waste and don’t have any hazardous liquid waste anymore!”
Jérôme Morinière, CEO, Advanced Identification Methods – AIM GmbH, Leipzig, Germany
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Chinese Academy of Tropical Agricultural Sciences
“We compared the EchoLUTION Plant DNA Kit with our established silica-technology based kit. Using the BioEcho kit we obtained genomic DNA in high yields much faster and easier than before. We were impressed about the simplicity of the whole process.”
Dr. Yang Yi, Environment and Plant Protection Institute, Chinese Academy of Tropical Agricultural Sciences
