Infectious Disease
Respiratory Viruses
Enteropathogenic Viruses
Respiratory Viruses
Overcome your respiratory viruses research challenges
Processing viral samples rapidly and mastering increases in the sample throughput is not without challenges. The laborious and time-consuming nucleic acid extraction procedures, time, and cost of upscaling, as well as supply chain issues are common bottlenecks.
BioEcho helps to overcome your respiratory viruses research challenges by providing today’s fastest and simplest viral nucleic acid extraction. Our solutions enable labs to scale up for high demands, to perform more tests in a shorter time, and to get answers faster.
Triple speed
Nucleic acids extraction three times faster with half the protocol steps of common methods.
Scale-up quickly
Massively increase throughput for peak sample demand.
Adaptable Throughput
Solution for small, middle- and high throughputs to scale up easily and provide flexibility in a cost-effective way.
Easy integration
Simple integration into your standard laboratory equipment.
Reduced consumable costs
Less consumable consumption due to fewer workflow steps compared to other methods.
Inhibitor-free nucleic acids
Highly pure respiratory virus RNA/DNA for reliable and reproducible RT-qPCR tests.
With the EchoLUTION technology, no incubation is needed for viral lysis. After a centrifugation step to prepare the column or plate, the purification is accomplished in a single one-minute centrifugation. Compared to silica-based methods using the bind–wash–elute principle that include several centrifugation steps, prolonging the workflow drastically.
Comparable performance
The clinical performance between EchoLUTION and a magnetic beads-based kit for the extraction of SARS-CoV-2 RNA is similar. The BioEcho viral kit (orange) and the magnetic beads kit (blue) were used to analyze 62 patients’ samples for the detection of the RdRP gene.
Solutions for respiratory virus research
Enteropathogenic Viruses
Shorten time to results with our single-step purification
Nucleic acid extraction is the first step in performing analyses based on RT-qPCR for determining the presence of a specific pathogen. Time-consuming and difficult nucleic acid extraction techniques can slow down the time to result.
BioEcho helps you to meet your enteropathogenic research challenges by providing today’s fastest and simplest viral nucleic acid extraction from stool samples. Our solutions enable research labs to easily scale up for high demands, to perform more tests in a shorter time and to get answers faster.
Get results faster
Reduce hands-on time with one-minute extraction technology.
Simplify workflows significantly
Nucleic acid extraction with half the steps of conventional methods.
Adapt throughput to your needs
Middle- and high-throughput solutions to scale up easily and provide flexibility in a cost-effective way.
Inhibitor-free nucleic acids
Highly pure viral RNA or DNA from enteropathogens for reliable and reproducible RT-qPCR tests.
Reduced consumable costs
Less consumption of consumables due to fewer workflow steps compared to other methods.
With the EchoLUTION technology, only 10 minutes incubation is needed for enteropathogenic viral lysis. After a centrifugation step to prepare the column or plate, the purification is accomplished in a single one-minute centrifugation. Compared to methods based on the bind–wash–elute principle including several centrifugation steps, the EchoLUTION technology is up to three times faster.
To evaluate our EchoLUTION technology, positive stool samples from patients were stored frozen and used to determine qPCR efficiency. The samples were validated for clinical diagnosis of adenovirus and rotavirus. Results confirmed that the EchoLUTION technology exhibited suitable efficiency, confirming that no inhibitors are present in the sample after nucleic acid extraction.
Robust qPCR efficiency
(RT)-qPCR of a dilution series from nucleic acids extracted using the EchoLUTION Viral RNA/DNA Kit. (RT)-qPCR quantification cycle (Ct) values are shown on a logarithmic scale. N = 8 replicates for each dilution and virus type.
The qPCR efficiency (%) has been calculated based on the slope of the log linear regression. Samples isolated with the EchoLUTION kit exhibit a reliable qPCR efficiency. Optimal efficiency lies between 90 – 110 %.
Enteropathogenic virus research solutions
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![MVZ Sonnen-Gesundheitszentrum SOGZ, Germany]()
MVZ Sonnen-Gesundheitszentrum SOGZ, Germany
“During the pandemic, we sequenced many SARS-CoV-2 samples to gain more insights on the genetic basis of current SARS-CoV-2 variants. Using the EchoLUTION Viral RNA/DNA Swab Kit significantly reduced the time required to extract the SARS-CoV-2 RNA and resulted in high-quality RNA to ensure robust sequencing results.”
Moritz Hass
Lab Manager, MVZ Sonnen-Gesundheitszentrum SOGZ, Germany -
![Bioanalysis, Limassol, Cyprus]()
Bioanalysis, Limassol, Cyprus
“Tourism is such an important industry for Cyprus and our laboratories must be as efficient as possible to deal with the huge numbers of passengers that visit our island every year. Thanks to the innovative extraction system of BioEcho, we have been able to eliminate bottlenecks at peak times and increase the overall efficiency of our COVID-19 PCR testing operations in a cost-effective manner without compromising the quality of our results”.
Dr. Christos Shammas,
Director of Bioanalysis, Limassol, Cyprus -
![Fenner laboratory, Germany]()
Fenner laboratory, Germany
“The automated RNA extraction workflow allowed us to process the large volumes of samples we received from hospitals and others much faster. The most important thing in fighting the Corona pandemic, especially at the beginning, was not to be able to send a positive result days later, but within 24 hours.”
Dr. Thomas Fenner,
Managing Director, Fenner laboratory, Germany
